BS PD CEN/TS 16826-2:2015

Molecular in vitro diagnostic examinations. Specifications for pre-examination processes for snap frozen tissue-Isolated proteins

BSI Group, 08/31/2015

Publisher: BS

File Format: PDF

$90.00$180.34


Published:31/08/2015

Pages:22

File Size:1 file , 1 MB

Note:This product is unavailable in Ukraine, Russia, Belarus

BS PD CEN/TS 16826-2:2015 gives recommendations for the handling, documentation and processing of frozen tissue specimens intended for the analysis of extracted proteins during the preanalytical phase before a molecular assay is performed. This Technical Specification is applicable to molecular in vitro diagnostic examinations (e.g., in vitro diagnostic laboratories, laboratory customers, developers and manufacturers of in vitro diagnostics, institutions and commercial organisations performing biomedical research, biobanks, and regulatory authorities).

Protein profiles and protein-protein interactions in tissues can change drastically before and after collection (due to e.g., gene induction, gene down regulation, protein degradation). Protein species amounts can change differently in tissues from different donors / patients. The expression of genes can be influenced by the given treatment or medical intervention (surgery, biopsy), or drugs administered for anaesthesia or even treatment of concomitant disease as well as by the different environment conditions after the tissue removal from the body.

Therefore, it is essential to take special measures to minimize the described profile changes and modifications within the tissue for subsequent protein analysis.

Tissues that have undergone chemical stabilization pre-treatment before freezing are not covered in this document. In addition this document is not applicable for protein analysis by immunohistochemistry.


Cross References:
EN ISO 15189:2012
ISO 15189:2012
ISO 15190
ISO Guide 30:1992


All current amendments available at time of purchase are included with the purchase of this document.

More BS standard pdf

BS 06/30142613 DC

BS 06/30142613 DC

ISO 23814. Cranes. Competency requirements for crane inspectors

$148.00 $297.41

BS 06/30135386 DC

BS 06/30135386 DC

BS 7959-3. Materials used for the control of liquid spillages. Part 3. Colour coding of sorbent materials

$142.00 $285.05

BS 06/30135205 DC

BS 06/30135205 DC

EN 15527.Characterization of waste. Determination of polycyclic aromatic hydrocarbons (PAH) in waste using gas Chromatography. Mass spectrometry (GC/MS)

$123.00 $247.92

BS 06/30150246 DC

BS 06/30150246 DC

ISO 16265-2. Water quality. Determination of methylene blue active substances (MBAS) index by flow analysis (CFA and FIA). Part 2. Method by continuous flow analysis (CFA)

$118.00 $237.44